A double signal electrochemical human immunoglobulin G immunosensor based on gold nanoparticles-polydopamine functionalized reduced graphene oxide as a sensor platform and AgNPs/carbon nanocomposite as signal probe and catalytic substrate
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- 作者：Si Zhang ; Na Huang ; Qiujun Lu ; Meiling Liu ; liumeilingww@126.com" class="auth_mail" title="E-mail the corresponding author ; Haitao Li ; Youyu Zhang ; Shouzhuo Yao
- 关键词：Double signal electrochemical immunosensor ; AuNPs-PDA-rGO ; Ag/C NC ; Sandwich-type immunoassay
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：77
- 期：Complete
- 页码：1078-1085
- 全文大小：3277 K
文摘
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A double signals immunosensor based on AuNPs-PDA-rGO and Ag/C NC was constructed.
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A great deal of Ab1 can be immobilized on AuNPs-PDA-rGO as the immobilizing platform.
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The signals were directly originated from Ag/C NC and indirectly result from the HQ.
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The results came from the double signals method were well consistent with each other.
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The proposed immunosensor was applied in the analysis of human IgG in real samples.