Effect of the meiotic inhibitor cilostamide on resumption of meiosis and cytoskeletal distribution in buffalo oocytes
详细信息 查看全文
- 作者：Qing-Yang Lia ; b ; Juan Loua ; Xiao-Gan Yanga ; Yang-Qing Lua ; Sheng-Sheng Lua ; shengshenglu@qq.com" class="auth_mail" title="E-mail the corresponding author ; Ke-Huan Lua ; khlu@gxu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Buffalo oocyte ; PDE3 inhibitor ; Microtubules ; Microfilaments ; Meiosis
- 刊名：Animal Reproduction Science
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：174
- 期：Complete
- 页码：37-44
- 全文大小：1433 K
文摘
- •
Addition of cilostamide to the pre-maturation culture arrests the resumption of meiosis.
- •
Prolonging the maturation culture period improves oocyte development in IVM.
- •
Dynamic changes in microtubules and microfilaments were similar to the control.
- •
Cilostamide didn’t adversely affect the in vitro maturation of oocytes and their subsequent embryo development.