Simultaneous quantification of 21 water soluble vitamin circulating forms in human plasma by liquid chromatography-mass spectrometry
详细信息 查看全文
- 作者：Karine Meisser Redeuila ; Karine.Meisser@rdls.nestle.com" class="auth_mail" title="E-mail the corresponding author ; Karin Longeta ; Sylvie Bé ; neta ; Caroline Munarib ; Esther Campos-Gimé ; neza
- 关键词：Water soluble vitamins ; Circulating forms ; Human plasma ; Liquid chromatography ; Tandem mass spectrometry
- 刊名：Journal of Chromatography A
- 出版年：2015
- 出版时间：27 November 2015
- 年：2015
- 卷：1422
- 期：Complete
- 页码：89-98
- 全文大小：678 K
文摘
- •
A novel separation is proposed to quantify 21 water soluble vitamin circulating forms.
- •
The acidified methanolic based sample preparation is combined with MS/MS detection.
- •
The analytical approach is validated for the quantification of 21 circulating forms in human plasma.
- •
We report the applicability of the methodology to real unknown human plasma samples.