Effect of sequencing of androgen deprivation and radiotherapy on prostate cancer growth

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• 作者：Kaminski ; Joseph M. L. ; Hanlon ; Alexandra L. ; Joon ; Daryl Lim ; Meistrich ; Marvin ; Hachem ; Paul ; et. al.
• 关键词：Radiotherapy ; Hormones ; Neoadjuvant ; Prostate ; Cancer
• 刊名：International Journal of Radiation Oncology*Biology*Physics
• 出版年：2003
• 出版时间：September 1, 2003
• 年：2003
• 卷：57
• 期：1
• 页码：24-28
• 全文大小：71.7 K

文摘

Androgen deprivation (AD) is frequently combined with radiotherapy (RT); however, the optimal sequence in vivo is currently unknown. Previous published work from our laboratory demonstrated that AD with RT was consistent with at least an additive, and possibly supra-additive, effect with the combined approach. We, therefore, performed additional experiments to elucidate the optimal sequence.