The Missing Niche for Spermatogonial Stem Cells: Do Blood Vessels Point the Way?

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• 作者：Gunapala Shetty ; Marvin L. Meistrich
• 刊名：Cell Stem Cell
• 出版年：2007
• 出版时间：11 October 2007
• 年：2007
• 卷：1
• 期：4
• 页码：361-363
• 全文大小：175 K

文摘

Although spermatogonial stem cell niches have been defined in lower organisms, their definitive localization in mammalian seminiferous tubules has been elusive. In a recent Science paper, Yoshida et al. (2007) elegantly demonstrated a vascular and interstitial tissue-associated niche for undifferentiated spermatogonia in the mouse.