Selective accumulation of the complement membrane attack complex in aging choriocapillaris
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- 作者：Kathleen R. Chirco ; Budd A. Tucker ; Edwin M. Stone ; Robert F. Mullins ; Robert-Mullins@uiowa.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Complement ; Choroid ; Choriocapillaris ; Age-related macular degeneration ; Microvasculature
- 刊名：Experimental Eye Research
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：393-397
- 全文大小：2420 K
文摘
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AMD is a degenerative disease with increased activation of complement in the choriocapillaris.
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The membrane attack complex was evaluated in human choroid and 19 other tissues.
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The labeling pattern observed for the membrane attack complex suggests the choroid is a hot spot for its deposition.