Microparticles for cell encapsulation and colonic delivery produced by membrane emulsification

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• 作者：S. Morelli ; R.G. Holdich ; M.M. Dragosavac ; ^{M.Dragosavac@lboro.ac.uk}
• 关键词：W/O emulsion ; water in oil emulsion ; G ; gelatin ; CS ; chitosan ; SPAN 80 ; Sorbitan monooleate 80 ; CV ; Coefficient of Variation ; Dav ; median average drop diameter ; SHMP ; sodium hexametaphosphate ; Tween 20 ; Polyethylene glycol sorbitan monolaurate ; PTFE ; Polytetrafluoroethylene ; FAS ; (Fluoro Alkyl Silane) ; ME ; membrane emulsification ; SPG membrane ; Shirasu-porous-glass membrane
• 刊名：Journal of Membrane Science
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：524
• 期：Complete
• 页码：377-388
• 全文大小：2931 K
• 卷排序：524

文摘

W/O emulsion drops produced by membrane emulsification contained up to 3×108 cells/mL. PTFE coated metal membrane, had high hydrophobicity and produced small drops. Gelatin and gelatin/chitosan microparticles were used to encapsulate yeast cells. Eudragit S100 coated particles provided targeted release in neutral/ basic conditions. Glucose consumption with time and live/dead staining confirmed cell viability.