ERBB3-rs2292239 as primary type 1 diabetes association locus among non-HLA genes in Chinese
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- 作者：Chengjun Suna ; 1 ; Haiyan Weib ; 1 ; Xiuli Chenc ; 1 ; Zhuhui Zhaoa ; Hongwei Dud ; Wenhui Songe ; Yu Yangf ; Miaoying Zhanga ; Wei Lua ; Zhou Peia ; Li Xia ; Jian Yang ; Dijing Zhia ; Ruoqian Chenga ; chengrq78@163.com" class="auth_mail" title="E-mail the corresponding author ; Feihong Luoa
- 关键词：Type 1 diabetes ; Genetic association ; Single nucleotide polymorphism ; ERBB3
- 刊名：Meta Gene
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：9
- 期：Complete
- 页码：120-123
- 全文大小：219 K
文摘
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A large scale case-control genetic association study on type 1 diabetes in Chinese investigating on-HLA genes.
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rs2292239 in the ERBB3 gene conferred the primary non-HLA association in Chinese type 1 diabetes.
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Markers in the common candidate genes, such as PTPN22, CTLA4, IL2RA, and INS, were not significantly associated with T1D in our Chinese cohort.