Eriocheir sinensis nascent polypeptide-associated complex alpha gene (EsNACA) was cloned.
EsNACA was constitutively expressed with dominant expression in hepatopancreas.
EsNACA gene expression was significantly altered by salinity and pH stresses.
EsNACA gene expression was significantly up-regulated by PAMPs and bacterial challenges.
EsNACA is an inducible gene involved in stress and immune response in crustaceans.