Heterogeneity of Mesp1+ mesoderm revealed by single-cell RNA-seq
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- 作者：Sunny Sun-Kin Chana ; b ; 1 ; sschan@umn.edu" class="auth_mail" title="E-mail the corresponding author ; Howe H.W. Chana ; 1 ; hw.chan@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Michael Kybaa ; b ; kyba@umn.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mesp1 ; Mesoderm patterning ; Cardiac development ; Hematopoiesis ; Single-cell RNA-seq
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：3 June 2016
- 年：2016
- 卷：474
- 期：3
- 页码：469-475
- 全文大小：2235 K
文摘
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A defined Mesp1 window promotes both hematopoietic and cardiac differentiation.
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Single-cell RNA-seq reveals heterogeneity of Mesp1+ mesoderm.
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Mesp1+ mesoderm contains a hematopoietic-primed and a cardiac-primed subset.