Simultaneous enantioselective determination of phenylpyrazole insecticide flufiprole and its chiral metabolite in paddy field ecosystem by ultra-high performance liquid chromatography/tandem mass spectrometry
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- 作者：Jing Lia ; 1 ; Yuting Zhanga ; 1 ; Youpu Chengb ; Shankui Yuanc ; Lei Liua ; Hui Shaoa ; Hui Lia ; Na Lia ; Pengyue Zhaoa ; Yongze Guoa ; yongze_guo@163.com" class="auth_mail" title="E-mail the corresponding author ; taas_jingli@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Flufiprole ; Chiral metabolite ; Enantioselective separation ; UPLC&ndash ; MS/MS ; Paddy field
- 刊名：Journal of Pharmaceutical and Biomedical Analysis
- 出版年：2016
- 出版时间：20 March 2016
- 年：2016
- 卷：121
- 期：Complete
- 页码：261-270
- 全文大小：1516 K
文摘
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Flufiprole and its chiral metabolite were baseline separated and enantioseparated.
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Optical pure stereoisomers were prepared and their elution order were distinguished.
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Clean-up/enrichment procedure was based on the modification of QuEChERS method.
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Cleanup step was further improved by solid phase extraction (SPE) technology.
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Analysis of samples was accomplished by chiral UPLC–MS/MS