Activity-dependent regulation of calcium and ribosomes in the chick cochlear nucleus
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- 作者：C.L. Call ; R.L. Hyson ; hyson@psy.fsu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：AIDA ; 1-Aminoindan-1 ; 5-dicarboxylic acid ; aCSF ; artificial cerebrospinal fluid ; ANOVA ; analysis of variance ; eEF-2 ; eukaryotic elongation factor-2 ; ERK-2 ; extracellular signal-regulated kinase 2 ; FMRP ; fragile X mental retardation protein ; mGluRs ; metabotropic glutamate receptors ; MCPG ; α-Methyl-4-carboxyphenylglycine ; NM ; nucleus magnocellularis ; NGS ; normal goat serum ; PBS ; phosphate-buffered saline ; Y10B-ir ; Y10B immunoreactivity
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：316
- 期：Complete
- 页码：201-208
- 全文大小：1049 K
文摘
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[Ca2+]i and ribosomes (Y10B-ir) show rapid changes in NM following deafferentation.
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There is a dissociation between how [Ca2+]i and ribosomes are regulated.
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Selective mGluR receptor blockade during stimulation dissociates the two events.
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Blockade of group I mGluRs affects changes in both [Ca2+]i and ribosomes.
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Blockade of group II mGluRs affects only ribosomal changes.