Mucin-secreting clear cell renal cell carcinoma. A rare variant of conventional renal cell carcinoma

详细信息    查看全文

• 作者：J. Fernando Val-Bernal ; MD ; PhD ; ^{apavbj@humv.es} ; Waleska Salcedo ; MD ; Daniel Val ; MD ; Alejandro Parra ; MD ; M. Francisca Garijo ; MD ; PhD
• 关键词：Cell modulation ; Clear cell renal cell carcinoma ; Conventional renal cell carcinoma ; Mucin secretion ; Mucin production ; Mucinous metaplasia
• 刊名：Annals of Diagnostic Pathology
• 出版年：2013
• 出版时间：April, 2013
• 年：2013
• 卷：17
• 期：2
• 页码：226-229
• 全文大小：1770 K

文摘

We report herein one case of conventional renal cell carcinoma (RCC) producing extensive extracellular mucinous secretion in a 71-year-old man. To the best of our knowledge, the presence of mucinous secretion in this tumor has not been documented. Mucin production, despite its low frequency, can be considered an additional feature of conventional RCC. Therefore, clear cell RCC should be added to the list of parenchymal renal tumors that can show significant mucin secretion; and it should be included in the inventory of morphologic variations of this tumor, which may cause diagnostic difficulties. It is of primary importance to distinguish mucin-secreting clear cell RCC from the metastasis of a mucin-secreting tumor to conventional RCC. Presence of mucin in a clear cell carcinoma does not exclude a renal origin.