Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma

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• 作者：Caroline Asirvatham Gjorup^a ; ^{caroline@gjorup.com} ; Helle Westergren Hendel^b ; Inge Marie Svane^c ; Lisbet Rosenkrantz Hö ; lmich^a
• 关键词：Melanoma ; FDG PET/CT ; Metastatic ; Intramuscular ; Masseter muscle ; T cell therapy
• 刊名：JPRAS Open
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：10
• 期：Complete
• 页码：1-4
• 全文大小：646 K
• 卷排序：10

文摘

A 65-year-old woman diagnosed with a nodular melanoma on the right shoulder had a PET/CT scan 13 months later demonstrating a FDG-avid mass in the left masseter muscle, which was asymptomatic and not clinically evident. Pathologic analysis confirmed metastasis of melanoma. Further subcutaneous, intramuscular and bone metastases developed and the patient was treated with surgery and immunotherapy. The patient is in complete-remission with no evident metastases seen on PET/CT 2.5 years after treatment with adoptive cell therapy using tumor-infiltrating lymphocytes (TIL therapy). Asymptomatic skeletal muscle metastases identified with PET/CT can have therapeutic and prognostic implications and a PET/CT scan should be performed as a true whole-body scan.