The stimulating role of subunit F in ATPase activity inside the A1-complex of the Methanosarcina mazei Gö1 A1AO ATP synthase
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- 作者：Dhirendra Singh ; Hendrik Sielaff ; Lavanya Sundararaman ; Shashi Bhushan ; Gerhard Grü ; ber ; ggrueber@ntu.edu.sg" class="auth_mail" title="E-mail the corresponding author
- 关键词：Subunit F ; A1AO ATP synthase ; ATP synthase ; Methanosarcina mazei Gö ; 1 ; Archaea ; Bioenergetics
- 刊名：Biochimica et Biophysica Acta (BBA) - Bioenergetics
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：1857
- 期：2
- 页码：177-187
- 全文大小：1891 K
文摘
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Enzymatic studies show that the M. mazei Gö1 A-ATP synthase subunit F is an ATPase activating subunit.
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Deletions of the N- or C-terminus of subunit F abolished the effect of ATP hydrolysis activation.
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Interaction of subunits B and F is proposed to affect the transition state, stabilized by the subunit B residue R349.