TEMPO-mediated aerobic oxidation of alcohols using copper(II) complex of bis(phenol) di-amine ligand as biomimetic model for Galactose oxidase enzyme

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• 作者：Elham Safaei^a ; ^b ; ^{e.safaei@shirazu.ac.ir" class="auth_mail" title="E-mail the corresponding author} ; Leila Hajikhanmirzaei^b ; Babak Karimi^b ; Andrzej Wojtczak^c ; Patricia Cotič^d ; Yong-Ill Lee^e
• 关键词：GOase ; Biomimetic copper complexes ; Phenoxyl radical ; Alcohol oxidation ; TEMPO
• 刊名：Polyhedron
• 出版年：2016
• 出版时间：26 February 2016
• 年：2016
• 卷：106
• 期：Complete
• 页码：153-162
• 全文大小：2786 K

文摘

Mononuclear copper complexes of four-dentate N₂O₂ bis(phenol) diamine ligands (H₂L^NEX X: C and OB in which C and OB are chloro and tert-butyl-methoxy substituents on phenol groups) have been synthesized and characterized by IR, UV–Vis, single crystal X-ray diffraction, magnetic susceptibility studies and cyclic voltammetry techniques. The CuL^NEX complexes show the square pyramid geometry of the coordination sphere with the copper centers surrounded by two nitrogen and oxygen atoms from the coordinating ligand and an axially bound water molecule. The effective magnetic moments of 1.7 and 1.8 BM confirm a monomer complex with copper(II) center. Electrochemical oxidation of these complexes yielded the corresponding Cu(II)-phenoxyl radical species. In addition, CuL^NEX complexes, have shown efficient catalytic activities for TEMPO-mediated oxidation of a set of alcohols to the corresponding aldehydes in the presence of molecular oxygen as oxidant at room temperature.