Counteraction of the deleterious effects of reactive oxygen species on hemoglobin structure and function by ellagic acid

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• 作者：Masoumeh Valipour^a ; ^b ; ^c ; Parvaneh Maghami^a ; ^d ; Mehran Habibi-Rezaei^e ; Mostafa Sadeghpour^f ; Mohamad Ali Khademian^g ; Khadijeh Mosavi^g ; Faizan Ahmad^h ; Ali Akbar Moosavi-Movahedi^a ; ^b ; ^{moosavi@ut.ac.ir}
• 关键词：MTBE ; methyl tert-butyl ether ; EA ; ellagic acid ; Hb ; hemoglobin ; ANS ; 1-anilinonaphthalene-8-sulfonic acid ; CD ; circular dichroism ; ROS ; reactive oxygen specious
• 刊名：Journal of Luminescence
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：182
• 期：Complete
• 页码：1-7
• 全文大小：1104 K
• 卷排序：182

文摘

Hemoglobin structure and function were disturbed in the presence of methyl tert-butyl ether (MTBE). Heme degradation was increased due to production of reactive oxygen specious. Deleterious effects of reactive oxygen specious were reduced by ellagic acid.