Translocation of 5′ mRNA cap analogue — peptide conjugates across the membranes of giant unilamellar vesicles
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- 作者：Remigiusz Worcha ; remiwo@ifpan.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Karolina Piecykb ; Anna Brygida Kolasaa ; Marzena Jankowska-Anyszkab ; c ; marzena@chem.uw.edu.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：MPS ; membrane permeable sequence ; m7G ; 7-methylguanosine ; m7GpppG ; P1-7-methylguanosine-5&prime ; P3-guanosine-5&prime ; triphosphate
- 刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：1858
- 期：2
- 页码：311-317
- 全文大小：993 K
文摘
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Translocation of peptide-nucleotide conjugates across membranes is studied in GUV.
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Membrane permeation sequence peptide shows translocation in contrast to conjugates.
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Use of artificial membranes complements cargo delivery studies in cells.