Unraveling the DNA Methylome in Mantle Cell Lymphoma: New Insights into the Cellular Origin

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• 作者：Larry Mansouri¹ ; Richard Rosenquist¹ ; ^{richard.rosenquist@igp.uu.se" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Cancer Cell
• 出版年：2016
• 出版时间：14 November 2016
• 年：2016
• 卷：30
• 期：5
• 页码：665-667
• 全文大小：461 K

文摘

Our understanding of the DNA methylome and its impact on cancer evolution and disease progression is rapidly evolving. In this issue of Cancer Cell, Queirós et al. provide a detailed characterization of the DNA methylome in mantle cell lymphoma and reveal novel molecular subtypes, potentially with different cellular origins.