How are comparative genomics and the study of microRNAs changing our views on arthropod endocrinology and adaptations to the environment?

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• 作者：Nathan J. Kenny^a ; ¹ ; Shan Quah^a ; ¹ ; Peter W.H. Holland^a ; ; Stephen S. Tobe^b ; ; Jerome H.L. Hui^a ; ^c ; ^{hui.jerome@gmail.com}
• 关键词：JH ; juvenile hormone ; MF ; methyl farnesoate ; NGS ; next generation sequencing ; JHAMT ; juvenile hormone methyltransferase ; FAMeT ; farnesoic acid O-methyltransferase ; SAM ; S-adenosyl-methyltransferase ; RNAi ; RNA interference
• 刊名：General and Comparative Endocrinology
• 出版年：2013
• 出版时间：1 July, 2013
• 年：2013
• 卷：188
• 期：Complete
• 页码：16-22
• 全文大小：639 K

文摘

As the last few decades of work has shown, precise regulation of biosynthesis and release of arthropod hormones is essential to cope with environmental stresses and challenges. In crustaceans and insects, the sesquiterpenoids methyl farnesoate (MF), farnesoic acid (FA) and juvenile hormone (JH) regulate many developmental, physiological, and reproductive processes. In this review, we discuss how comparative genomics has and will impact our views on arthropod endocrinology. We will also highlight the current knowledge of regulation of genes involved in arthropod hormone biosynthesis by microRNAs, and describe the potential insights into arthropod endocrinology, evolution, and adaptation that are likely to come from the study of microRNAs.