mGluR1/5 activation in the lateral hypothalamus increases food intake via the endocannabinoid system
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- 作者：Asai Sá ; nchez-Fuentesa ; Bruno A. Marichal-Cancinoa ; Mó ; nica Mé ; ndez-Dí ; aza ; Alline L. Becerril-Melé ; ndeza ; Alejandra E. Ruiz-Contrerasb ; Oscar Prospé ; ro-Garciaa ; opg@unam.mx" class="auth_mail" title="E-mail the corresponding author
- 关键词：2-AG ; Food intake-lateral hypothalamus ; mGluR1/5 ; Endocannabinoid system
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：19 September 2016
- 年：2016
- 卷：631
- 期：Complete
- 页码：104-108
- 全文大小：795 K
文摘
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Suppression of diacylglycerol lipase in the lateral hypothalamus prevented the increment in food intake induced by CHPG (mGluR1/5 agonist).
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Blockade of CB1 receptors (with AM251) in the lateral hypothalamus prevented the increment in food intake induced by CHPG (mGluR1/5 agonist).
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Lateral hypothalamic activation of mGluR1/5 increase food intake via endocannabinoid system.