Hox Function Is Required for the Development and Maintenance of the Drosophila Feeding Motor Unit
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- 作者：Jana Friedrich1 ; Sebastian Sorge1 ; Fatmire Bujupi1 ; Michael P. Eichenlaub2 ; Natalie G. Schulz1 ; Jochen Wittbrodt2 ; Ingrid Lohmann1 ; ilohmann@flydev.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Drosophila ; neuromuscular unit ; Hox ; hatching behavior ; feeding behavior ; feeding movements ; Deformed (Dfd) ; feeding motor pattern ; motor control ; Hox4 ; Ank2-XL ; synapse ; neuromuscular junction
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：2 February 2016
- 年：2016
- 卷：14
- 期：4
- 页码：850-860
- 全文大小：4306 K
文摘
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Hox gene Dfd is critical for feeding motor patterns in Drosophila
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Dfd instructs motor unit formation via stage- and tissue-specific target genes
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Synaptic specificity is dependent on actions of Dfd in motor neurons and muscles
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Maintenance of synapses is directly regulated by Dfd