Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit
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- 作者：Nicole A. Crowley1 ; 2 ; Daniel W. Bloodgood1 ; 2 ; J. Andrew Hardaway2 ; Alexis M. Kendra2 ; Jordan G. McCall3 ; 4 ; 5 ; Ream Al-Hasani4 ; 5 ; Nora M. McCall2 ; Waylin Yu1 ; 2 ; Zachary L. Schools4 ; Michael J. Krashes7 ; 8 ; 9 ; Bradford B. Lowell7 ; 10 ; Jennifer L. Whistler11 ; Michael R. Bruchas3 ; 4 ; 5 ; Thomas L. Kash2 ; 6 ; tkash@med.unc.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：29 March 2016
- 年：2016
- 卷：14
- 期：12
- 页码：2774-2783
- 全文大小：2849 K
文摘
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KORs presynaptically inhibit BLA glutamate transmission in the BNST
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Optogenentic activation of local dynorphin neurons produces inhibition of glutamate
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Deletion of amygdala KORs produces an anxiolytic phenotype in the elevated plus maze