Towards a molecular-level theory of carbohydrate processivity in glycoside hydrolases
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- 作者：Gregg T Beckham1 ; Gregg.Beckham@nrel.gov" class="auth_mail ; Jerry Stå ; hlberg2 ; Jerry.Stahlberg@slu.edu" class="auth_mail ; Brandon C Knott1 ; Michael E Himmel3 ; Michael F Crowley3 ; Mats Sandgren2 ; Morten Sø ; rlie4 ; Christina M Payne5 ; 6 ; Christy.Payne@uky.edu" class="auth_mail
- 刊名：Current Opinion in Biotechnology
- 出版年：June 2014
- 年：2014
- 卷：27
- 期：Complete
- 页码：96-106
- 全文大小：1963 K
文摘
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Processive glycoside hydrolases provide significant hydrolytic potential.
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Newly developed cellulose and chitin processivity measurement methods are reviewed.
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We propose processivity mechanisms in GH6 and GH7 cellulases from structural data.
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A framework is developed for a thermodynamic and kinetic theory of GH processivity.