Gradient enhanced-fluidity liquid hydrophilic interaction chromatography of ribonucleic acid nucleosides and nucleotides: A “green” technique
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- 作者：Michael C. Beilke ; Martin J. Beres ; Susan V. Olesik ; olesik.1@osu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hydrophilic interaction liquid chromatography ; Enhanced-fluidity liquid chromatography ; Nucleosides ; Nucleotides ; Green chemistry
- 刊名：Journal of Chromatography A
- 出版年：2016
- 出版时间：4 March 2016
- 年：2016
- 卷：1436
- 期：Complete
- 页码：84-90
- 全文大小：824 K
文摘
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Gradient enhanced-fluidity liquid chromatography (EFLC) of nucleosides and nucleotides was studied.
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EFLC mobile phases offered higher separation speed than conventional HPLC counterpart.
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EFLC provides “greener” methods than HPLC with acetonitrile/water.