文摘
Small renal masses (SRMs) are defined as enhancing kidney tumours ≤4 cm that are usually incidentally detected. Most, but not all, are RCCs.. SRMs are usually treated as presumed RCC. As a result, benign tumours and low grade RCCs of uncertain biology are being treated in over 20% of cases. Pretreatment renal tumour biopsy (RTB) can reduce potentially unnecessary treatment, but is not widely practiced yet. RTB is safe, with only a 1% incidence of significant complications, has a high diagnostic yield and accuracy, and is cost effective. RTB, together with molecular and genetic studies will improve our knowledge of SRMs and has the potential of risk-adapted personalized treatment