Cell wall hydrolases and antibiotics: exploiting synergy to create efficacious new antimicrobial treatments
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- 作者：Michael Wittekind mwittekind@contrafect.com" class="auth_mail" title="E-mail the corresponding author ; Raymond Schuch
- 刊名：Current Opinion in Microbiology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：33
- 期：Complete
- 页码：18-24
- 全文大小：851 K
文摘
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Cell wall hydrolases can have bactericidal activities.
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Cell wall hydrolases can display synergy with other antimicrobials.
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Synergies found with antibiotics, antimicrobial peptides, and enzymes.
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Synergy mechanisms include enhanced penetration of weakened cell walls.
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Studies exploring synergy with cell wall hydrolases are reviewed.