Synthesis of a d-rhamnose branched tetrasaccharide, repeating unit of the O-chain from Pseudomonas syringae pv. Syringae (cerasi) 435

详细信息    查看全文

• 作者：Bedini ; Emiliano ; Carabellese ; Antonella ; Michela Corsaro ; Maria ; De Castro ; Cristina ; Parrilli ; Michelangelo
• 关键词：O-Chain ; Pseudomonas cerasi ; Repeating unit ; D-Rhamnose ; Oligosaccharide ; Synthesis
• 刊名：Carbohydrate Research
• 出版年：2004
• 出版时间：August 2, 2004
• 年：2004
• 卷：339
• 期：11
• 页码：1907-1915
• 全文大小：346 K

文摘

The first synthesis of a d-rhamnose branched tetrasaccharide, corresponding to the repeating unit of the O-chain from Pseudomonas syringae pv. cerasi 435, as methyl glycoside is reported. The approach used is based on the synthesis of an opportune building-block, that is the methyl 3-O-allyl-4-O-benzoyl-α-d-rhamnopyranoside, which was then converted into both a glycosyl acceptor and two different protected glycosyl trichloroacetimidate donors. Successive couplings of these three compounds afforded the target oligosaccharide. The reported synthesis is also useful to perform the oligomerization of the repeating unit.