Dysregulation of brain stress systems mediates compulsive alcohol drinking

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• 作者：Brendan J Tunstall¹ ; ² ; Stephanie A Carmack¹ ; ² ; George F Koob¹ ; Leandro F Vendruscolo¹ ; ^{leandro.vendruscolo@nih.gov}
• 刊名：Current Opinion in Behavioral Sciences
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：13
• 期：Complete
• 页码：85-90
• 全文大小：310 K
• 卷排序：13

文摘

Disruption of HPA axis leads to reward system hypofunction in alcohol dependence. Extrahypothalamic stress systems are sensitized in alcohol dependence. Loss of reward and stress sensitization drive compulsive alcohol drinking.