Statistical evaluation and discrimination of competing kinetic models and hypothesis for the mathematical description of poly-3(hydroxybutyrate) synthesis by Cupriavidus necator DSM 545

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• 作者：Daniela E.G. Trigueros^a ; ^{estelita_trigueros@yahoo.com.br} ; Camila L. Hinterholz^a ; Mô ; nica L. Fiorese^a ; Glá ; ucia M.F. Aragã ; o^b ; Willibaldo Schmidell^b ; Maria A.M. Reis^c ; Alexander D. Kroumov^d
• 关键词：Competing kinetic models ; Cupriavidus necator ; PHB ; Genetic algorithms ; Statistical tests ; Stoichiometry of the bioprocess
• 刊名：Chemical Engineering Science
• 出版年：2017
• 出版时间：16 March 2017
• 年：2017
• 卷：160
• 期：Complete
• 页码：20-33
• 全文大小：1622 K
• 卷排序：160

文摘

Use of statistical analysis strategy for the discrimination of competing microbial growth models. The phenomenological modeling approach is formulated to describe PHB synthesis by C. necator. The stoichiometry of the microbial growth and PHB synthesis is correlated to the kinetics studies. The statistical approach of evaluation built a base for deeper understanding of the oxygen transfer. The response surface analysis and stoichiometric balance are used to simulated OUR and OTR.