Marked elevation of urinary β2-microglobulin in patients with reversible splenial lesions: A small case series
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- 作者：Junji Azumaa ; jjazuma2009@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Shin Nabatameb ; Toshiya Katsuraa ; Kyoko Yamamotoa ; Hiroshi Kanenoa ; Eri Kijimaa ; Yoshimi Mizoguchia ; Tunesuke Shimotsujia ; Takehisa Yamamotoa ; Keiichi Ozonob
- 关键词：ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; β2MG ; β2-microglobulin ; CK ; creatine kinase ; CLEIA ; chemiluminescence enzyme immunoassay ; DWI ; diffusion-weighted Image ; EEG ; electroencephalography ; ELISA ; immunosorbent assay ; GTC ; generalized tonic&ndash ; clonic seizures ; IFN ; interferon ; IL ; Interleukin ; IVIG ; intravenous immunoglobulin ; MERS ; clinically mild encephalitis/encephalopathy with a reversible splenial lesion ; MHC ; major histocompatibility complex ; mPSL ; methylpredniso
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 September 2016
- 年：2016
- 卷：368
- 期：Complete
- 页码：109-112
- 全文大小：337 K
文摘
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We report four patients with reversible splenial lesions.
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All four cases showed markedly increased urinary β2-microglobulin (β2MG) levels.
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Elevated urinary β2MG may reflect an excessive immune response.
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20">Excessive immune response might play a role in the pathogenesis of reversible splenial lesions.