A quantitative peptidomics approach to unravel immunological functions of angiotensin converting enzyme in Locusta migratoria
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- 作者：Tewodros Firdissa Duressaa ; tedifir@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Kurt Boonenb ; kurt.boonen@bio.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ; Roger Huybrechtsa ; Roger.Huybrechts@bio.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ;
- 关键词：Insect ; Angiotensin converting enzyme ; ACE ; Locusta migratoria ; Hemocyanin
- 刊名：General and Comparative Endocrinology
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：235
- 期：Complete
- 页码：120-129
- 全文大小：1351 K
文摘
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Locust orthologue of angiotensin converting enzyme (LmACE) is an extracellular protein encoded by multiple exons.
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Following LPS or PGN challenge, LmACE transcript was upregulated in hemocytes but not in fat body.
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Differential peptidomics of peptides in circulation unraveled putative enzymatic roles of LmACE.