Quinolines: Microwave-assisted synthesis and their antifungal, anticancer and radical scavenger properties

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• 作者：Natá ; lia Aparecida Liberto^a ; Juliana Baptista Simõ ; es^a ; Sarah de Paiva Silva^a ; Cristiane Jovelina da Silva^b ; Luzia Valentina Modolo^b ; Â ; ngelo de Fá ; tima^c ; Luciana Maria Silva^d ; Marcos Derita^e ; Susana Zacchino^e ; Omar Miguel Portilla Zuñ ; iga^f ; Gustavo Pablo Romanelli^f ; Sergio Antonio Fernandes^a ; ^{santonio@ufv.br} ; ^{sefernandes@gmail.com}
• 关键词：Quinoline ; Antifungal ; Anticancer ; Antioxidant ; Calix[n]arenes
• 刊名：Bioorganic & Medicinal Chemistry
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：25
• 期：3
• 页码：1153-1162
• 全文大小：1766 K
• 卷排序：25

文摘

An efficient method for the synthesis of quinolines using microwave irradiation was developed providing 28 quinolines with good yields. The reaction procedures are environmentally friendly, convenient, mild and of easy work-up. Quinolines were evaluated for their antifungal, anticancer and antioxidant properties and exhibited high activities in all tests performed.