Chronic consumption of an inositol-enriched beverage ameliorates endothelial dysfunction and oxidative stress in type 2 diabetes
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- 作者：Antonio Herná ; ndez-Mijaresa ; b ; c ; d ; hernandez_antmij@gva.es" class="auth_mail" title="E-mail the corresponding author ; Celia Bañ ; ulsa ; b ; c ; Susana Rovira-Llopisa ; b ; c ; Á ; ngeles Á ; lvareze ; f ; Samuel Ordene ; f ; Olalla Rubio-Pucholb ; Ví ; ctor M. Ví ; ctora ; b ; c ; e ; g ; victor.victor@uv.es" class="auth_mail" title="E-mail the corresponding author ; Milagros Rochaa ; b ; c ; e ; milagros.rocha@uv.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Apo ; apolipoprotein ; BMI ; body mass index ; CGMS ; control glucose monitoring system ; CMFDA ; 5-chloromethyl fluorescein diacetate ; CVD ; cardiovascular disease ; DCFH-DA ; 2&prime ; 7&prime ; -dichlorodihydrofluorescein diacetate ; DPBS ; Dulbecco's phosphate buffered saline ; EGM-2 ; endothelial cell growth medium ; GSH ; reduced glutathione ; HbA1c ; glycated haemoglobin ; HBSS ; Hank's balanced salt solution ; HDLc ; high density lipoprotein cholesterol ; HOMA-IR ; homeostasis model assessment of insulin resistanc
- 刊名：Journal of Functional Foods
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：18
- 期：part_PA
- 页码：598-607
- 全文大小：1356 K
文摘
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The effect of inositols on glycaemia, endothelial function and redox status was assessed.
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This was a 12-week, randomized, double-blind controlled trial in DM subjects.
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Inositols reduced glycated haemoglobin and postprandial and nocturnal glycaemia.
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Inositols improved endothelial function and intracellular redox status.