Breast cancer metastasis burden in sentinel nodes analysed using one-step nucleic acid amplification predicts axillary nodal status
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- 作者：Thomas D. Milnera ; b ; tommilner1@doctors.org.uk" class="auth_mail" title="E-mail the corresponding author ; Simon de Lusignanb ; Simon Jonesb ; Peter A. Jacksona ; Graham T. Layera ; b ; Mark W. Kissina ; Tracey E. Irvinea
- 关键词：Breast cancer ; One-step nucleic acid amplification (OSNA) ; Sentinel lymph node
- 刊名：The Breast
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：24
- 期：5
- 页码：568-575
- 全文大小：810 K
文摘
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NSLN metastasis risk in breast cancer patients undergoing SLNB analysis using OSNA.
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Categorising by extent of sentinel node positivity predicts NSLN metastasis risk.
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A multiple incomplete positive SLNB of micrometastases has low NSLN metastasis risk.
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SLNB metastasis size better predicts NSLN involvement than total CK-19 mRNA count.