Serology-Based Diagnostics for the Control of Bovine Neosporosis

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• 作者：Stefano Guido¹ ; ² ; ^{stefano.guido@moredun.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Frank Katzer¹ ; Ian Nanjiani³ ; Elspeth Milne² ; Elisabeth A. Innes¹
• 关键词：Neospora ; neosporosis ; diagnostics ; cattle ; control.
• 刊名：Trends in Parasitology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：32
• 期：2
• 页码：131-143
• 全文大小：2077 K

文摘

The protozoan Neospora caninum is a primary infectious cause of abortion in cattle that causes significant economic losses worldwide. Because effective vaccines and licensed pharmacological treatments are currently unavailable, control measures rely on biosecurity and management practice. Serological diagnosis plays a crucial role in the identification of infected animals and several tests have been developed. However, owing to the particular dynamics of the host–parasite interaction and to the characteristics of the currently used diagnostic tools, a proportion of infected cattle may not be reliably identified, and can potentially undermine efforts towards the control of bovine neosporosis. Current diagnostic methods for N. caninum infection in cattle and the advances necessary to support effective control strategies are discussed.