Genomic features of human limb specific enhancers

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• 作者：Shahid Ali^a ; ^{Shahidbsb28@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Bibi Amina^a ; ^{bbamina120@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Saneela Anwar^b ; ^{amirsanila@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Rashid Minhas^a ; ^{minhas61@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Nazia Parveen^a ; ^{naziaahmad.nm@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Uzma Nawaz^c ; ^{uzm_69@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Syed Sikandar Azam^b ; ^{ssazam@qau.edu.pk" class="auth_mail" title="E-mail the corresponding author} ; Amir Ali Abbasi^a ; ^{abbasiam@qau.edu.pk" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Limbs ; Enhancers ; Genomics ; Regulatory networks ; Transcriptional factor ; Development ; disease
• 刊名：Genomics
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：108
• 期：3-4
• 页码：143-150
• 全文大小：766 K

文摘

<dl class="listitem" id="list_l0005"><dt class="label">•dt><dd>

d="p0005">Specific target genes are pinpointed for human limb specific enhancers.

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d="p0010">Modular organization of enhancers may contribute in limb evolution.

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d="p0015">Range of action of limb specific enhancers is defined.

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d="p0020">Heterotypic interactions of multiple distinct TFs govern the limb morphogenesis.

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