Bioactive isopimarane diterpenoids from the stems of Euonymus oblongifolius

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• 作者：Fei Li ; Jie Ma ; Chuang-Jun Li ; Jing-Zhi Yang ; Dan Zhang ; Xiao-Guang Chen ; Dong-Ming Zhang ; ^{zhangdm@imm.ac.cn}
• 关键词：Euonymus oblongifolius ; Celastraceae ; Isopimarane diterpenoid ; Nitric oxide production ; Cytotoxicity
• 刊名：Phytochemistry
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：135
• 期：Complete
• 页码：144-150
• 全文大小：665 K
• 卷排序：135

文摘

Seven isopimarane diterpenes and one abietane diterpene together with six known sesquiterpenes were isolated. The absolute configuration of 1 was determined by single-crystal X-ray crystallographic analysis. Inhibitory ability against LPS-induced nitric oxide production and cytotoxicity against A549 cell line growth.