Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade
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- 作者：Zhaolin Chena ; b ; 1 ; Tianlu Shia ; b ; 1 ; Lei Zhanga ; Pengli Zhua ; Mingying Denga ; Cheng Huangb ; Tingting Hub ; Ling Jianga ; ahslyyjl@126.com" class="auth_mail" title="E-mail the corresponding author ; Jun Lib ; lj@ahmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; anhuimedi1311@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：3&prime ; -UTR ; 3&prime ; -untranslated region ; ABC ; ATP-binding cassette ; ATP ; adenosine triphosphate ; BCR-ABL ; breakpoint cluster region-Abelson ; BCRP/ABCG2 ; breast cancer resistance protein ; BMP4 ; bone morphogenetic protein 4 ; BrTet ; 5-bromotetrandrine ; cMOAT ; canalicular multispecific organic anion transporter ; COX-2 ; cyclo-oxygenase-2 ; DNMT ; DNA methyltransferase ; DVL1 ; dishevelled-1 ; EGCG ; (&minus ; )-epigallocatechin-3-gallate ; EGFR ; epidermal growth factor receptor ; EZH2 ; histone-lysine N-meth
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：370
- 期：1
- 页码：153-164
- 全文大小：626 K
文摘
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Overview of ABC transporters in the role of MDR.
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Inhibitors of ABC transporters will be useful tools in the modulation of MDR.
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Recent developments of RNA interference which involved in ABC transporter-mediated MDR.
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Epigenetic regulators exhibit effective function on the ABC transporter-mediated MDR.