DNA-PKcs-PIDDosome: A Nuclear Caspase-2-Activating Complex with Role in G2/M Checkpoint Maintenance

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• 作者：Mingan Shi ; Carolyn J. Vivian ; Kyung-Jong Lee ; Chunmin Ge ; Keiko Morotomi-Yano ; Claudia Manzl ; Florian Bock ; Shigeo Sato ; Chieri Tomomori-Sato ; Ruihong Zhu ; Jeffrey S. Haug ; Selene K. Swanson ; Michael
• 刊名：Cell
• 出版年：2009
• 出版时间：6 February 2009
• 年：2009
• 卷：136
• 期：3
• 页码：508-520
• 全文大小：2398 K

文摘

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).

This article has been retracted at the request of the Authors.

Our paper reported the identification of a nuclear protein complex comprising DNA-PKcs, PIDD, and caspase-2 and characterization of its role in G2/M checkpoint maintenance, thereby providing insight into the functional significance of nuclear caspase-2. We recently identified errors affecting several figure panels where original data were processed inappropriately such that the figure panels do not accurately report the original data. We believe that the most responsible course of action is to retract the paper. We sincerely apologize to the scientific community for any inconvenience this might cause.