Long-term low-dose 伪-particle enhanced the potential of malignant transformation in human bronchial epithelial cells through MAPK/Akt pathway
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- 作者：Weili Liu ; Linlin Xiao ; Chen Dong ; Mingyuan He ; Yan Pan ; Yuexia Xie ; Wenzhi Tu ; Jiamei Fu ; Chunlin Shao ; clshao@shmu.edu.cn" class="auth_mail
- 关键词：Long-term low dose radiation ; 伪-Particle ; Malignant transformation ; MAPK/Akt
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：9 May 2014
- 年：2014
- 卷：447
- 期：3
- 页码：388-393
- 全文大小：1178 K
文摘
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Multi-exposures of 25 mGy 伪-ray enhanced cell proliferation, adhesion, and invasion.
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MAPK/Akt but not JNK/P66 was positively correlated with cell invasive phenotypes.
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LDR of 伪-irradiation triggers cell malignant transformation through MAPK/Akt.