T helper (Th)-cytokines in the urine of patients with primary glomerulonephritis treated with immunosuppressive drugs: Can they predict outcome?
详细信息 查看全文
- 作者：Dimitra Kalavriziotia ; dkalavrizioti@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Miltiadis Gerolymosa ; 1 ; mgerolymos@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Maria Rodib ; 1 ; marodi_biol@yahoo.gr" class="auth_mail" title="E-mail the corresponding author ; Pantelitsa Kalliakmania ; pkalliak@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Simela Provatopouloua ; simellap@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Theodoros Eleftheriadisc ; teleftheriadis@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Athanasia Mouzakib ; mouzaki@upatras.gr" class="auth_mail" title="E-mail the corresponding author ; Dimitrios S. Goumenosa ; dgoumenos@upatras.gr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Th ; T helper ; IL ; interleukin ; IFN-纬 ; interferon gamma ; TNF-伪 ; tumour necrosis factor alpha ; TGF-尾1 ; transforming growth factor beta 1 ; GN ; glomerulonephritides ; IgAN ; immunoglobulin A nephropathy ; MN ; membranous nephropathy ; MCD ; minimal change disease ; FSGS ; focal segmental glomerulosclerosis ; CBA ; cytometric bead array ; ELISA ; enzyme-linked immunosorbent assay ; M ; male ; F ; female
- 刊名：Cytokine
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：76
- 期：2
- 页码：260-269
- 全文大小：964 K
文摘
- •
Higher levels of urinary excretion of Th-cytokines and MCP-1 in GN patients.
- •
Most urinary Th-cytokines increased even in patients in clinical remission.
- •
Strong positive correlation between MCP-1 and TGF-尾1 urinary levels.
- •
Higher TGF-尾1 and MCP-1 levels in MN patients with a progressive clinical course.