Normal Movement Selectivity in Autism

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• 作者：Ilan Dinstein ; Cibu Thomas ; Kate Humphreys ; Nancy Minshew ; Marlene Behrmann ; David J. Heeger
• 刊名：Neuron
• 出版年：2010
• 出版时间：13 May 2010
• 年：2010
• 卷：66
• 期：3
• 页码：461-469
• 全文大小：969 K

文摘

Summary

It has been proposed that individuals with autism have difficulties understanding the goals and intentions of others because of a fundamental dysfunction in the mirror neuron system. Here, however, we show that individuals with autism exhibited not only normal fMRI responses in mirror system areas during observation and execution of hand movements but also exhibited typical movement-selective adaptation (repetition suppression) when observing or executing the same movement repeatedly. Movement selectivity is a defining characteristic of neurons involved in movement perception, including mirror neurons, and, as such, these findings argue against a mirror system dysfunction in autism.

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