Acceptability of the levonorgestrel intrauterine system in the long-term treatment of heavy menstrual bleeding: how many women choose to use a second device?

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• 作者：I&#xf1 ; aki Lete ; ^a ; ^{ilete@hsan.osakidetza.net} ; Marí ; a del Carme Cuesta^a ; Juan M. Marí ; n^a ; Miguel Martí ; nez^a ; Asunci&#xf3 ; n Bermejo^a ; Roberto Arina^a
• 关键词：Contraceptive agents/female ; therapeutic use ; Levonorgestre/therapeutic use ; Menorrhagia/drug therapy ; Intrauterine devices ; medicated
• 刊名：European Journal of Obstetrics and Gynecology and Reproductive Biology
• 出版年：2011
• 出版时间：January 2011
• 年：2011
• 卷：154
• 期：1
• 页码：67-70
• 全文大小：113 K

文摘

lass=""h4"">Objective

To assess the acceptability of the levonorgestrel-releasing intrauterine system (LNG-IUS, Mirena^®) in the long-term treatment of heavy menstrual bleeding.

lass=""h4"">Study design

Retrospective study of all consecutive women who had a LNG-IUS inserted for control of idiopathic heavy menstrual bleeding between January 2000 and December 2003. Duration of use, reasons for early removal, number of devices removed after 5 years of use, and number of women who decided to use a second LNG-IUS were assessed.

lass=""h4"">Results

Of a total of 216 devices inserted, 129 (59.7 % ) were removed after 5 years of use, 68 (31.5 % ) were removed anytime before the completion of 5 years, and the remaining 19 (8.8 % ) patients were lost to follow-up. In 32 of the 68 cases (47.1 % ) with early removal of the LNG-IUS, the main reason for discontinuation was the appearance of the menopause. After the 5-year effective lifetime of the LNG-IUS, 51 of the 129 women (39.5 % ) chose to have a second device inserted. Of the 78 women who completed the 5-year treatment period and did not decide to use the LNG-IUS again, 71 (91 % ) had reached the menopause.

lass=""h4"">Conclusion

The LNG-IUS was well accepted by women with idiopathic heavy menstrual bleeding as shown by 39.5 % of users (or 87.9 % if menopausal women are excluded) deciding to use a second device when the first LNG-IUS expired after 5 years of use.