Amidine derivatives of α-arylglycines from N-(1-aryl-2,2,2-trichloroethyl)amides of arenesulfonic acids and secondary amines

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• 作者：Igor B. Rozentsveig ; Galina G. Levkovskaya ; Gulnur N. Rozentsveig ; Anna N. Mirskova ; Leonid B. Krivdin ; Ludmila I. Larina and Aleksandr I. Albanov
• 关键词：Amidines ; Sulfonamides ; Chloroaziridines ; Secondary amines
• 刊名：Tetrahedron Letters
• 出版年：2005
• 出版时间：19 December 2005
• 年：2005
• 卷：46
• 期：51
• 页码：8889-8893
• 全文大小：228 K

文摘

The interaction of N-(1-aryl-2,2,2-trichloroethyl)amides of arenesulfonic acids with secondary amines or their salts in the presence of inorganic bases involves the formation of chloroaziridine intermediates. Depending upon the solvent and reagent ratio, the reaction results in N-[1-dialkylamino-2-chloro-2-arylethylidene]-, N-[2-dialkylamino-1-chloro-2-arylethylidene]-, N-[1,2-bis(dialkylamino)-2-arylethylidene]-, and N-(1,2-dioxo-2-arylethene)amides of arenesulfonic acids.