Mechanisms of protein misfolding: Novel therapeutic approaches to protein-misfolding diseases
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- 作者：Parveen Salahuddina ; Mohammad Khursheed Siddiqia ; Sanaullah Khanb ; Ali Saber Abdelhameedc ; Rizwan Hasan Khana ; rizwanhkhan@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; rizwanhkhan1@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Protein-misfolding ; Amyloid ; Oxidative stress ; Aggregation ; Error in trafficking
- 刊名：Journal of Molecular Structure
- 出版年：2016
- 出版时间：5 November 2016
- 年：2016
- 卷：1123
- 期：Complete
- 页码：311-326
- 全文大小：1607 K
文摘
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Protein misfolding occurs due to formation of non-native structure of protein.
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Environmental conditions and other factors influences the misfolding of protein.
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Protein misfolding usually followed by aggregation.
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Therapeutics are effective partially to treat aggregate associated disorders.