刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:1 January 2017
年:2017
卷:482
期:1
页码:62-67
全文大小:594 K
卷排序:482
文摘
During aging there is a widespread and progressive accumulation of misfolded protein aggregates. Treatment or worms with protein aggregation inhibitors substantially increase animal lifespan. Lifespan elongation was paralleled by an increase of healthspan in treated worms. Our findings open a new strategy to increase longevity and enhance quality of life during aging.