Stiffness Parameter 尾 of Cardioembolism Measured by Carotid Ultrasound Was Lower Than Other Stroke Subtypes

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• 作者：Hidetaka Mitsumura ; MD ; ^{hmitsumura@jikei.ac.jp" class="auth_mail} ; Kenichi Sakuta ; MD ; Keiko Bono ; MD ; Mikihiro Yamazaki ; MD ; Renpei Sengoku ; MD ; Yu Kono ; MD ; Tsutomu Kamiyama ; MD ; Masahiko Suzuki ; MD ; Hiroshi Furuhata ; MD ; PhD ; Yasuyuki Iguchi ; MD
• 关键词：Ultrasonography ; arterial stiffness ; atherosclerosis ; stroke subtype
• 刊名：Journal of Stroke and Cerebrovascular Diseases
• 出版年：July 2014
• 年：2014
• 卷：23
• 期：6
• 页码：1391-1395
• 全文大小：273 K

文摘

We estimated the stiffness parameter 尾 (尾 value), which is useful in the assessment of premature atherosclerosis, among patients with different subtypes of cerebral infarction (CI; eg, small-vessel occlusion, large-artery atherosclerosis, cardioembolism, and other determined and undetermined etiologies) to determine the clinical utility of the 尾 value in classification of stroke patients into CI subtypes.

Methods

Carotid ultrasonography (ALOKA ProSound SSD-alpha10) was performed in 31 CI patients and 38 control subjects, and the 尾 value of the bilateral common carotid artery at 2.0 cm proximal to the bifurcation was measured using the echo-tracking method. The relationship between 尾 value and age was examined, and the 尾 value was compared among the different CI subtypes.

Results

Positive 尾 value correlated with age in control subjects (R = .69, P < .001) but not in CI patients (R = −.01, P = .996). There was no significant difference in the 尾 value when comparing control patients and patients with cardioembolic stroke (P = .106), but the 尾 value were lower in patients with cardioembolic stroke than in patients with noncardioembolic stroke (eg, small-vessel occlusion, large-artery atherosclerosis, and others, P = .009).

Conclusions

The 尾 value was lower in patients with cardioembolic stroke than in patients with noncardioembolic stroke. The 尾 value may be useful for estimating the risk of different stroke subtypes.