Effects of Cardiac Resynchronization Therapy on the Doppler Tei Index

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• 作者：Toshinori Yuasa ; MD ; PhD ; Chinami Miyazaki ; MD ; Jae K. Oh ; MD ; FACC ; Raul E. Espinosa ; MD ; Charles J. Bruce ; MD ; FACC ; ^{bruce.charles@mayo.edu}
• 关键词：Cardiac resynchronization therapy ; Doppler Tei index ; Left ventricular function ; Myocardial performance ; Right ventricular function
• 刊名：Journal of the American Society of Echocardiography
• 出版年：2009
• 出版时间：March 2009
• 年：2009
• 卷：22
• 期：3
• 页码：253-260
• 全文大小：650 K

文摘

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Background

The Tei index is an indicator of systolic and diastolic myocardial performance. We evaluated the Tei index in patients undergoing cardiac resynchronization therapy (CRT).

Methods

Forty-two patients were studied before CRT and 1 day and 6 months after CRT, comparing responders with nonresponders.

Results

The Tei index decreased 1 day after CRT (left ventricle [LV]: P < .001, right ventricle [RV]: P = .01) and remained lower at follow-up (LV and RV: P < .001 vs baseline). Responders had a higher LV Tei index at baseline (P = .003) and achieved a sustained improvement in Tei index at follow-up (LV: P < .001, RV: P = .002) in contrast with nonresponders (LV and RV: not significant). Baseline LV Tei index and change in LV Tei index were both correlated with LV end-systolic volume reduction after CRT (r = 0.52, P < .001, r = 0.43, P = .006).

Conclusion

The baseline LV Tei index was significantly higher in responders and exhibited an acute and sustained improvement after CRT. The baseline RV Tei index was similar in responders and nonresponders but improved significantly only in responders.