Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development
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- 作者：Neil A. Barrett1 ; 4 ; Camille Malouf1 ; 2 ; 4 ; Chrysa Kapeni1 ; 2 ; Wendi A. Bacon1 ; George Giotopoulos1 ; Sten Eirik W. Jacobsen3 ; Brian J. Huntly1 ; Katrin Ottersbach1 ; 2 ; katrin.ottersbach@ed.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：26 July 2016
- 年：2016
- 卷：16
- 期：4
- 页码：1039-1054
- 全文大小：5726 K
文摘
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Mll-AF4 confers enhanced B cell potential and causes an expansion of pro-B cells
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Mll-AF4 increases self-renewal potential
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Mll-AF4 exerts its effects in a restricted developmental window
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The LMPP is a potential cell of origin for Mll-AF4-associated disease